CN Patent

CN103351347A — 盐酸苯达莫司汀杂质dce的制备方法

Assigned to Southeast University · Expires 2013-10-16 · 13y expired

What this patent protects

本发明公开了一种盐酸苯达莫司汀杂质DCE的制备方法，以[1-甲基-2-(4’-丁酸乙酯基)-5-氨基]-1H-苯并咪唑为起始原料制备[1-甲基-2-(4’-丁酸基)-5-N-(2’-氯乙基)]-1H-苯并咪唑，即DCE。本发明方法制备盐酸苯达莫司杂质DCE，具有制备方法简单、所得产品纯度较高的优点，为盐酸苯达莫司汀的质量控制提供合格的对照品。

USPTO Abstract

本发明公开了一种盐酸苯达莫司汀杂质DCE的制备方法，以[1-甲基-2-(4’-丁酸乙酯基)-5-氨基]-1H-苯并咪唑为起始原料制备[1-甲基-2-(4’-丁酸基)-5-N-(2’-氯乙基)]-1H-苯并咪唑，即DCE。本发明方法制备盐酸苯达莫司杂质DCE，具有制备方法简单、所得产品纯度较高的优点，为盐酸苯达莫司汀的质量控制提供合格的对照品。

Drugs covered by this patent

bendamustine-hydrochloride (BENDAMUSTINE HYDROCHLORIDE)

Patent Metadata

Patent number: CN103351347A
Jurisdiction: CN
Classification: —
Expires: 2013-10-16
Drug substance claim: No
Drug product claim: No
Assignee: Southeast University
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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