CA Patent

CA2290509A1 — 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as mek inhibitors

Assigned to Warner Lambert Co LLC · Expires 1999-01-14 · 27y expired

What this patent protects

Phenylamino benzoic acid, benzamides, and benzyl alcohol derivatives of formula (I) where R1, R2, R3, R4, R5, and R6 are hydrogen or substituent groups such as alkyl, and where R7 is hydrogen or an organic radical, and Z is COOR7, tetrazolyl, CONR6R7, or CH2OR7, are potent inhibi…

USPTO Abstract

Phenylamino benzoic acid, benzamides, and benzyl alcohol derivatives of formula (I) where R1, R2, R3, R4, R5, and R6 are hydrogen or substituent groups such as alkyl, and where R7 is hydrogen or an organic radical, and Z is COOR7, tetrazolyl, CONR6R7, or CH2OR7, are potent inhibitors of MEK and, as such, are effective in treating cancer and other proliferative diseases such as inflammation, psoriasis and restenosis, as well as stroke, heart failure, and immunodeficiency disorders.

Drugs covered by this patent

Patent Metadata

Patent number
CA2290509A1
Jurisdiction
CA
Classification
—
Expires
1999-01-14
Drug substance claim
No
Drug product claim
No
Assignee
Warner Lambert Co LLC
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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