CA2231050A1 — System for rendering substantially non-dissoluble bio-affecting agents bio-available
Assigned to BIOVAIL INTERNATIONAL Ltd · Expires 1997-03-13 · 29y expired
What this patent protects
The present invention is a method of preparing a system for delivering a bio-affecting agent and the composition prepared thereby. The invention includes forming a solid dispersion of the bio-affecting agent in an increased energy state in a water-soluble polymer which is compati…
USPTO Abstract
The present invention is a method of preparing a system for delivering a bio-affecting agent and the composition prepared thereby. The invention includes forming a solid dispersion of the bio-affecting agent in an increased energy state in a water-soluble polymer which is compatible with the bio-affecting agent. As a consequence of transforming the bio-affecting agent to an increased-energy condition and freezing it in such condition in a water-soluble polymer, the bio-affecting agent is made available ("bio-available") to a bio-system upon dissolution of the polymer. This method and composition has been found extremely effective for delivery of otherwise substantially non-soluble drugs and other bio-affecting ingredients.
Drugs covered by this patent
- Mektovi (binimetinib) · Pfizer
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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