How many antibody-drug conjugates drugs are tracked?

Drug Landscape tracks 17 antibody-drug conjugates (15 marketed, 1 Phase 3, 0 Phase 2, 1 Phase 1).

How fresh is this page?

Refreshed every 30 minutes from primary sources (Drugs@FDA, EMA EPAR, ClinicalTrials.gov, sponsor 8-K filings).

Antibody-Drug Conjugates — Pipeline, Approvals, Sponsors

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

ADCs combine an antibody (targeting moiety) with a cytotoxic payload via a chemical linker. Enhertu (T-DXd) and Trodelvy lead the space. Rapid growth in oncology with multiple second-generation payloads.

Marketed

Filed

Phase 3

Phase 2

Phase 1

Total

Marketed leaders

2021-01-01 — LONCASTUXIMAB TESIRINE · Antibody-Drug Conjugate (ADC) · Oncology
2020-01-01 — SACITUZUMAB GOVITECAN
2020-01-01 — Blenrep · GSK · Oncology
2019-01-01 — Enfortumab · Astellas Pharma · Oncology
2019-01-01 — TRASTUZUMAB DERUXTECAN
2019-01-01 — ENFORTUMAB VEDOTIN
2019-01-01 — Polivy · Roche · Oncology
2018-01-01 — Lumoxiti · AstraZeneca · Oncology
2017-01-01 — INOTUZUMAB OZOGAMICIN · CD22-directed Immunoconjugate [EPC] · Oncology
2017-01-01 — Besponsa · Pfizer · Antibody-drug conjugate (ADC) · Oncology
2013-01-01 — TRASTUZUMAB EMTANSINE
2011-01-01 — BRENTUXIMAB VEDOTIN · CD30-directed Immunoconjugate [EPC]

Recent approvals (last 30 days)

No approvals in the last 30 days.

Upcoming PDUFA (next 180 days)

No upcoming PDUFA in next 180 days.

Top sponsors in this modality

· 10 antibody-drug conjugates
Pfizer Inc. · 2 antibody-drug conjugates
AstraZeneca · 1 antibody-drug conjugates
Pfizer · 1 antibody-drug conjugates
Roche · 1 antibody-drug conjugates
GSK · 1 antibody-drug conjugates
Astellas Pharma · 1 antibody-drug conjugates

Drug classes within Antibody-Drug Conjugates

Antibody-drug conjugate (ADC) · 2
Antibody-Drug Conjugate (ADC) · 1
CD22-directed Immunoconjugate [EPC] · 1
CD30-directed Immunoconjugate [EPC] · 1
CD33-directed Immunoconjugate [EPC] · 1

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Other modalities

Biologics Monoclonal Antibodies Small Molecules Cell Therapies Gene Therapies Gene Editing mRNA Therapeutics siRNA Therapeutics Antisense Oligonucleotides Bispecific Antibodies Vaccines

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing