Generic entry timeline

MACIMORELIN ACETATE generics — when can they launch?

MACIMORELIN ACETATE (MACIMORELIN ACETATE) · · 1 active US patent · 0 expired

Earliest patent expiry
2027-10-12
1 year remaining
Full patent estate to
2027-10-12
complete protection through 2027
FDA approval
2017

Where MACIMORELIN ACETATE sits in the generic timeline

Imminent generic cliff: earliest active US patent for MACIMORELIN ACETATE expires in 2027 (~1 year from today). ANDA filers are likely already preparing Paragraph IV certifications. Expect first-filer 180-day exclusivity competition imminently.

Under US Hatch-Waxman, a generic enters via an ANDA (Abbreviated New Drug Application) and may file with one of four Paragraph IV certifications attacking the brand's listed patents. If the brand sues within 45 days, a 30-month FDA approval stay is triggered. First Para IV filer typically gets 180-day market exclusivity.

Patent estate by type — active patents

Method-of-use patents only carve out specific indications; generics can launch with a "skinny label" omitting those uses. Composition-of-matter patents block the molecule itself.

  • Method of Use — 1 patent

FDA U-codes carved out by MACIMORELIN ACETATE patents

Method-of-use patents are listed against specific FDA Patent Use Codes ("U-codes") representing carved-out indications. Generics can launch with a label that omits these uses.

U-codeDescription
U-2220(no description)

Sample patent estate

Showing 1 of 1 active US patents. View full estate on the MACIMORELIN ACETATE drug page →

  • US8192719 Method of Use · expires 2027-10-12
    This patent protects a method for diagnosing growth hormone deficiency in humans or animals by orally administering EP 1572 or EP 1573 and measuring growth hormone levels.
    USPTO title: Methods and kits to diagnose growth hormone deficiency by oral administration of EP 1572 or EP 1573 compounds

Sources

Patent term extensions (PTR, pediatric exclusivity), Hatch-Waxman 30-month stays, and FDA regulatory exclusivity (NCE/ODE/PED) may shift the effective generic entry date. Not legal advice.

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