US Patent

US8192719 — Methods and kits to diagnose growth hormone deficiency by oral administration of EP 1572 or EP 1573 compounds

Method of Use · Assigned to Aeterna Zentaris GmbH · Expires 2027-10-12 · 1y remaining

Vulnerability score 75/100 Vulnerable — likely target for IPR or design-around

What this patent protects

This patent protects a method for diagnosing growth hormone deficiency in humans or animals by orally administering EP 1572 or EP 1573 and measuring growth hormone levels.

USPTO Abstract

A method of assessing growth hormone deficiency in a human or animal subject, the method comprising administering orally to the subject EP 1572 (Formula I) or EP 1573 (Formula II), obtaining a post-administration sample from the subject, determining the level of growth hormone in the sample and assessing whether the level of growth hormone in the sample is indicative of growth hormone deficiency in the subject. Preferably, the GH level in the sample is measured by immunoassay. Also disclosed is a kit of parts constituting a diagnostic kit comprising: (a) EP 1572 or EP 1573 formulated for oral administration; and (b) means for determining the level of growth hormone in a sample.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-2220 macimorelin-acetate

Patent Metadata

Patent number
US8192719
Jurisdiction
US
Classification
Method of Use
Expires
2027-10-12
Drug substance claim
No
Drug product claim
No
Assignee
Aeterna Zentaris GmbH
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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