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ZYDENA TAB.75mg(Udenafil 75mg)

Samsung Medical Center · FDA-approved active Small molecule

Udenafil inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum, increasing cyclic GMP levels to promote smooth muscle relaxation and penile erection.

Udenafil inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum, increasing cyclic GMP levels to promote smooth muscle relaxation and penile erection. Used for Erectile dysfunction.

At a glance

Generic nameZYDENA TAB.75mg(Udenafil 75mg)
SponsorSamsung Medical Center
Drug classPhosphodiesterase type 5 (PDE5) inhibitor
TargetPDE5 (phosphodiesterase type 5)
ModalitySmall molecule
Therapeutic areaUrology / Sexual Health
PhaseFDA-approved

Mechanism of action

As a PDE5 inhibitor, udenafil prevents the breakdown of cyclic guanosine monophosphate (cGMP), allowing sustained smooth muscle relaxation in penile tissue. This enhances blood flow to the corpus cavernosum in response to sexual stimulation, facilitating erectile function. Udenafil has a longer half-life compared to some other PDE5 inhibitors, providing extended therapeutic duration.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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