{"id":"zydena-tab-75mg-udenafil-75mg","safety":{"commonSideEffects":[{"rate":"10-15","effect":"Headache"},{"rate":"5-10","effect":"Flushing"},{"rate":"5-10","effect":"Dyspepsia"},{"rate":"5-10","effect":"Nasal congestion"},{"rate":"2-5","effect":"Back pain"},{"rate":"2-5","effect":"Myalgia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a PDE5 inhibitor, udenafil prevents the breakdown of cyclic guanosine monophosphate (cGMP), allowing sustained smooth muscle relaxation in penile tissue. This enhances blood flow to the corpus cavernosum in response to sexual stimulation, facilitating erectile function. Udenafil has a longer half-life compared to some other PDE5 inhibitors, providing extended therapeutic duration.","oneSentence":"Udenafil inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum, increasing cyclic GMP levels to promote smooth muscle relaxation and penile erection.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:39:50.702Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Erectile dysfunction"}]},"trialDetails":[{"nctId":"NCT03142542","phase":"PHASE4","title":"The Efficacy and Safety of Udenafil in Patients With Erectile Dysfunction After Bilateral Nerve-sparing Radical Prostatectomy","status":"UNKNOWN","sponsor":"Samsung Medical Center","startDate":"2017-05","conditions":"Prostate Cancer With Radical Prostatectomy","enrollment":99}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"ZYDENA TAB.75mg(Udenafil 75mg)","genericName":"ZYDENA TAB.75mg(Udenafil 75mg)","companyName":"Samsung Medical Center","companyId":"samsung-medical-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Udenafil inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum, increasing cyclic GMP levels to promote smooth muscle relaxation and penile erection. Used for Erectile dysfunction.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}