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Zocular Eyelid System Treatment
The Zocular Eyelid System Treatment is a thermal pulsation device that applies controlled heat and pressure to the eyelids to liquefy and express meibum from blocked meibomian glands.
The Zocular Eyelid System Treatment is a thermal pulsation device that applies controlled heat and pressure to the eyelids to liquefy and express meibum from blocked meibomian glands. Used for Meibomian gland dysfunction, Evaporative dry eye disease.
At a glance
| Generic name | Zocular Eyelid System Treatment |
|---|---|
| Also known as | ZEST |
| Sponsor | Uptown Eye Specialists |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
The device uses localized heating and mechanical pulsation to warm the lipid secretions within meibomian glands, reducing their viscosity and allowing them to be expressed more effectively. This restores the lipid layer of the tear film, which is essential for tear stability and reducing evaporative dry eye symptoms. By clearing gland obstruction and improving meibum quality, the treatment addresses the underlying pathophysiology of meibomian gland dysfunction.
Approved indications
- Meibomian gland dysfunction
- Evaporative dry eye disease
Common side effects
- Eyelid erythema
- Transient discomfort during treatment
- Mild eyelid edema
Key clinical trials
- The Effect of a Pre-cataract Surgical Ocular Hygiene Regime on Microbial Load, Tear Osmolarity, Dry Eye, and Inflammatory Markers (PHASE4)
- Meibomian Gland Dysfunction Management With ZEST Protocol (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Zocular Eyelid System Treatment CI brief — competitive landscape report
- Zocular Eyelid System Treatment updates RSS · CI watch RSS
- Uptown Eye Specialists portfolio CI