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Zinc Oxide and Avobenzone
Zinc oxide and avobenzone work together as a broad-spectrum sunscreen by reflecting and absorbing ultraviolet radiation to protect skin from sun damage.
Zinc oxide and avobenzone work together as a broad-spectrum sunscreen by reflecting and absorbing ultraviolet radiation to protect skin from sun damage. Used for Sunburn prevention and UV protection.
At a glance
| Generic name | Zinc Oxide and Avobenzone |
|---|---|
| Sponsor | University of California, Davis |
| Drug class | Sunscreen / UV protective agent |
| Modality | Small molecule |
| Therapeutic area | Dermatology / Preventive Care |
| Phase | FDA-approved |
Mechanism of action
Zinc oxide is a physical (mineral) sunscreen that reflects and scatters both UVA and UVB rays. Avobenzone is a chemical sunscreen that absorbs UVA radiation, particularly in the UVA-I range. Together, they provide complementary protection across the full UV spectrum to prevent sunburn, photoaging, and skin cancer risk.
Approved indications
- Sunburn prevention and UV protection
Common side effects
- Skin irritation or sensitization
- Allergic contact dermatitis (avobenzone)
- White cast or residue on skin (zinc oxide)
Key clinical trials
- Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light (NA)
- Determination of Sun Protection in Sunscreen Formulas (Study SR09-15)(P08236)(COMPLETED) (PHASE3)
- Ultraviolet and UV-Visible Light Photoprotection for the Treatment of Melasma (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Zinc Oxide and Avobenzone CI brief — competitive landscape report
- Zinc Oxide and Avobenzone updates RSS · CI watch RSS
- University of California, Davis portfolio CI