{"id":"zinc-oxide-and-avobenzone","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation or sensitization"},{"rate":null,"effect":"Allergic contact dermatitis (avobenzone)"},{"rate":null,"effect":"White cast or residue on skin (zinc oxide)"}]},"_chembl":null,"_dailymed":{"setId":"ebaf5ef7-84aa-4cb1-a701-2e0d0fd357df","title":"DIY BOOSTER SPF 30 FACIAL SERUM UNSCENTED (OCTINOXATE, OCTISALATE, AVOBENZONE, AND ZINC OXIDE) LOTION [ANDALOU NATURALS]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Zinc oxide is a physical (mineral) sunscreen that reflects and scatters both UVA and UVB rays. Avobenzone is a chemical sunscreen that absorbs UVA radiation, particularly in the UVA-I range. Together, they provide complementary protection across the full UV spectrum to prevent sunburn, photoaging, and skin cancer risk.","oneSentence":"Zinc oxide and avobenzone work together as a broad-spectrum sunscreen by reflecting and absorbing ultraviolet radiation to protect skin from sun damage.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T04:29:39.827Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Sunburn prevention and UV protection"}]},"trialDetails":[{"nctId":"NCT05865431","phase":"NA","title":"Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light","status":"COMPLETED","sponsor":"University of California, Davis","startDate":"2017-03-17","conditions":"Sun Damaged Skin","enrollment":17},{"nctId":"NCT01001975","phase":"PHASE3","title":"Determination of Sun Protection in Sunscreen Formulas (Study SR09-15)(P08236)(COMPLETED)","status":"COMPLETED","sponsor":"Bayer","startDate":"2009-07","conditions":"Sun Protection","enrollment":10},{"nctId":"NCT01695356","phase":"PHASE4","title":"Ultraviolet and UV-Visible Light Photoprotection for the Treatment of Melasma","status":"COMPLETED","sponsor":"Universidad Autonoma de San Luis Potosí","startDate":"2012-09","conditions":"Melasma","enrollment":68}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":16,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Zinc Oxide and Avobenzone","genericName":"Zinc Oxide and Avobenzone","companyName":"University of California, Davis","companyId":"university-of-california-davis","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Zinc oxide and avobenzone work together as a broad-spectrum sunscreen by reflecting and absorbing ultraviolet radiation to protect skin from sun damage. Used for Sunburn prevention and UV protection.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}