Last reviewed · How we verify
Z. officinale extract
Zingiber officinale (ginger) extract exerts anti-inflammatory and antioxidant effects through inhibition of prostaglandin and leukotriene synthesis and free radical scavenging.
Zingiber officinale (ginger) extract exerts anti-inflammatory and antioxidant effects through inhibition of prostaglandin and leukotriene synthesis and free radical scavenging. Used for Nausea and vomiting, Dyspepsia and gastrointestinal discomfort, Inflammatory conditions.
At a glance
| Generic name | Z. officinale extract |
|---|---|
| Sponsor | Fundação Educacional Serra dos Órgãos |
| Drug class | Herbal extract / Natural product |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology / Anti-inflammatory |
| Phase | FDA-approved |
Mechanism of action
Ginger extract contains active compounds (gingerols and shogaols) that inhibit cyclooxygenase and 5-lipoxygenase enzymes, reducing inflammatory mediator production. It also possesses antioxidant properties that neutralize reactive oxygen species, contributing to its anti-inflammatory and gastroprotective effects.
Approved indications
- Nausea and vomiting
- Dyspepsia and gastrointestinal discomfort
- Inflammatory conditions
Common side effects
- Gastrointestinal upset
- Heartburn
- Allergic reactions (rare)
Key clinical trials
- Effectiveness and Safety of Zingiber Officinale Transdermal Patch for Acne Vulgaris; Study of Interleukin 1 and Skin Microbiome (PHASE2, PHASE3)
- Clinical Evaluation of the Use of Ginger Extract in the Management of Motion Sickness (PHASE4)
- Cinnamon and Ginger in Comparison to Chlorhexidine Gluconate 0.2% on Oral Streptococcus Mutans (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Z. officinale extract CI brief — competitive landscape report
- Z. officinale extract updates RSS · CI watch RSS
- Fundação Educacional Serra dos Órgãos portfolio CI