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Xenon vs propofol
Xenon is a general anesthetic that works by modulating the activity of N-methyl-D-aspartate (NMDA) receptors in the brain.
Xenon is a general anesthetic that works by modulating the activity of N-methyl-D-aspartate (NMDA) receptors in the brain. Used for General anesthesia for surgical procedures.
At a glance
| Generic name | Xenon vs propofol |
|---|---|
| Sponsor | Rigshospitalet, Denmark |
| Drug class | General anesthetic |
| Target | NMDA receptor |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | Phase 3 |
Mechanism of action
Xenon's mechanism of action is thought to involve the blockade of NMDA receptors, which are involved in the regulation of consciousness and memory. This blockade leads to a decrease in the excitability of neurons, resulting in a loss of consciousness. Additionally, xenon may also have a role in the modulation of other receptors, such as the GABA_A receptor, which can contribute to its anesthetic effects.
Approved indications
- General anesthesia for surgical procedures
Common side effects
- Respiratory depression
- Hypotension
- Nausea and vomiting
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |