{"id":"xenon-vs-propofol","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Respiratory depression"},{"rate":"10-20%","effect":"Hypotension"},{"rate":"5-10%","effect":"Nausea and vomiting"}]},"_chembl":{"chemblId":"CHEMBL526","moleculeType":"Small molecule","molecularWeight":"178.27"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Xenon's mechanism of action is thought to involve the blockade of NMDA receptors, which are involved in the regulation of consciousness and memory. This blockade leads to a decrease in the excitability of neurons, resulting in a loss of consciousness. Additionally, xenon may also have a role in the modulation of other receptors, such as the GABA_A receptor, which can contribute to its anesthetic effects.","oneSentence":"Xenon is a general anesthetic that works by modulating the activity of N-methyl-D-aspartate (NMDA) receptors in the brain.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:41:06.901Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"General anesthesia for surgical procedures"}]},"trialDetails":[{"nctId":"NCT00192959","phase":"PHASE3","title":"Xenon Inhalation During Orthopaedic Surgery in Elderly Subjects.","status":"COMPLETED","sponsor":"Rigshospitalet, Denmark","startDate":"2004-03","conditions":"Anaesthesia, Postoperative Cognitive Function","enrollment":44}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Xenon vs propofol","genericName":"Xenon vs propofol","companyName":"Rigshospitalet, Denmark","companyId":"rigshospitalet-denmark","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Xenon is a general anesthetic that works by modulating the activity of N-methyl-D-aspartate (NMDA) receptors in the brain. Used for General anesthesia for surgical procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}