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VYD2311-MD

Invivyd, Inc. · Phase 3 active Small molecule ✓ Verified May 2026

VYD2311-MD is a monoclonal antibody Small molecule drug developed by Invivyd, Inc.. It is currently in Phase 3 development for Prevention of COVID-19.

VYD2311-MD is a monoclonal antibody that targets the SARS-CoV-2 spike protein.

VYD2311-MD is a small molecule being studied in a Phase 3 clinical trial for the prevention of COVID-19. The trial is a randomized, triple-blind, placebo-controlled study evaluating the efficacy and safety of VYD2311-MD in adults and adolescents.

Likelihood of approval
60.3% vs 58.3% industry baseline
If approved by FDA: likely 2028–2030
Steps remaining: NDA/BLA submission
Confidence: High
Why this estimate
  • Baseline phase 3 → approval rate +58.3pp
    Industry-wide phase 3 drugs reach approval ~58.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
  • Anti-infectives pathway favourability +2.0pp
    Microbiological endpoints + non-inferiority designs raise approval rates above baseline.
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2028–2030
EMA EU 2029–2031 +0.7 yr
MHRA GB 2029–2031 +0.7 yr
Health Canada CA 2029–2032 +0.9 yr
TGA AU 2029–2032 +1.2 yr
PMDA JP 2029–2032 +1.5 yr
NMPA CN 2030–2033 +2.3 yr
MFDS KR 2029–2032 +1.4 yr
CDSCO IN 2029–2033 +1.8 yr
ANVISA BR 2030–2033 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameVYD2311-MD
SponsorInvivyd, Inc.
Drug classmonoclonal antibody
TargetSARS-CoV-2 spike protein
ModalitySmall molecule
Therapeutic areaInfectious Disease
PhasePhase 3

Mechanism of action

It works by binding to the spike protein, preventing the virus from entering host cells. This mechanism of action is similar to other COVID-19 vaccines, but the specific details of VYD2311-MD's mechanism may differ slightly.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about VYD2311-MD

What is VYD2311-MD?

VYD2311-MD is a monoclonal antibody drug developed by Invivyd, Inc., indicated for Prevention of COVID-19.

How does VYD2311-MD work?

VYD2311-MD is a monoclonal antibody that targets the SARS-CoV-2 spike protein.

What is VYD2311-MD used for?

VYD2311-MD is indicated for Prevention of COVID-19.

Who makes VYD2311-MD?

VYD2311-MD is developed by Invivyd, Inc. (see full Invivyd, Inc. pipeline at /company/invivyd-inc).

What drug class is VYD2311-MD in?

VYD2311-MD belongs to the monoclonal antibody class. See all monoclonal antibody drugs at /class/monoclonal-antibody.

What development phase is VYD2311-MD in?

VYD2311-MD is in Phase 3.

What are the side effects of VYD2311-MD?

Common side effects of VYD2311-MD include Pain, redness, or swelling at the injection site, Fatigue, Headache.

What does VYD2311-MD target?

VYD2311-MD targets SARS-CoV-2 spike protein and is a monoclonal antibody.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing