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Verapamil HEXAL (verapamil)
Verapamil blocks L-type calcium channels in cardiac and vascular smooth muscle, reducing calcium influx and decreasing heart rate, contractility, and blood pressure.
Verapamil blocks L-type calcium channels in cardiac and vascular smooth muscle, reducing calcium influx and decreasing heart rate, contractility, and blood pressure. Used for Hypertension, Angina pectoris, Supraventricular tachycardia.
At a glance
| Generic name | Verapamil HEXAL (verapamil) |
|---|---|
| Also known as | Verapamil HEXAL |
| Sponsor | Zealand University Hospital |
| Drug class | Calcium channel blocker (non-dihydropyridine) |
| Target | L-type calcium channel |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
Verapamil is a non-dihydropyridine calcium channel blocker that inhibits the inward movement of calcium ions through L-type calcium channels in the sinoatrial and atrioventricular nodes, as well as in vascular smooth muscle. This action slows conduction through the AV node, reduces myocardial contractility, and causes vasodilation, resulting in decreased heart rate and blood pressure. These effects make it useful for treating hypertension, angina, and certain arrhythmias.
Approved indications
- Hypertension
- Angina pectoris
- Supraventricular tachycardia
- Atrial fibrillation rate control
Common side effects
- Constipation
- Dizziness
- Headache
- Fatigue
- Bradycardia
- Hypotension
- Edema
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Verapamil HEXAL (verapamil) CI brief — competitive landscape report
- Verapamil HEXAL (verapamil) updates RSS · CI watch RSS
- Zealand University Hospital portfolio CI