Last reviewed · How we verify
Vanish XT Dental Varnish
Vanish XT Dental Varnish is a Topical fluoride varnish Small molecule drug developed by University of Nebraska. It is currently FDA-approved for Dental caries prevention, Enamel remineralization, Dentin hypersensitivity management. Also known as: resin-modified glass ionomer.
Vanish XT is a fluoride varnish that adheres to tooth surfaces to provide sustained fluoride release for caries prevention and remineralization.
Vanish XT is a fluoride varnish that adheres to tooth surfaces to provide sustained fluoride release for caries prevention and remineralization. Used for Dental caries prevention, Enamel remineralization, Dentin hypersensitivity management.
At a glance
| Generic name | Vanish XT Dental Varnish |
|---|---|
| Also known as | resin-modified glass ionomer |
| Sponsor | University of Nebraska |
| Drug class | Topical fluoride varnish |
| Target | Tooth enamel (hydroxyapatite) |
| Modality | Small molecule |
| Therapeutic area | Dental/Preventive Dentistry |
| Phase | FDA-approved |
Mechanism of action
The varnish formulation allows prolonged contact between fluoride and tooth enamel, promoting remineralization of early carious lesions and strengthening enamel against acid attack. The sticky resin base keeps the fluoride in contact with teeth longer than rinses or gels, enhancing bioavailability and protective effects.
Approved indications
- Dental caries prevention
- Enamel remineralization
- Dentin hypersensitivity management
Common side effects
- Mild tooth staining or discoloration
- Temporary unpleasant taste
- Mild gum irritation
Key clinical trials
- Effectiveness of Resin-Modified Glass Ionomer Varnish in Preventing White Spot Lesions in Fixed Appliance Orthodontia (PHASE4)
- Effectiveness of Using (Vanish XT) in Prevention of Occlusal Caries: a RCT (NA)
- Effect of Light Curable Resin Modified Glass Ionomer Varnish on Non-Cavitated Proximal Carious Lesions' Progression (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Vanish XT Dental Varnish CI brief — competitive landscape report
- Vanish XT Dental Varnish updates RSS · CI watch RSS
- University of Nebraska portfolio CI
Frequently asked questions about Vanish XT Dental Varnish
What is Vanish XT Dental Varnish?
How does Vanish XT Dental Varnish work?
What is Vanish XT Dental Varnish used for?
Who makes Vanish XT Dental Varnish?
Is Vanish XT Dental Varnish also known as anything else?
What drug class is Vanish XT Dental Varnish in?
What development phase is Vanish XT Dental Varnish in?
What are the side effects of Vanish XT Dental Varnish?
What does Vanish XT Dental Varnish target?
Related
- Drug class: All Topical fluoride varnish drugs
- Target: All drugs targeting Tooth enamel (hydroxyapatite)
- Manufacturer: University of Nebraska — full pipeline
- Therapeutic area: All drugs in Dental/Preventive Dentistry
- Indication: Drugs for Dental caries prevention
- Indication: Drugs for Enamel remineralization
- Indication: Drugs for Dentin hypersensitivity management
- Also known as: resin-modified glass ionomer
- Compare: Vanish XT Dental Varnish vs similar drugs
- Pricing: Vanish XT Dental Varnish cost, discount & access