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Tryparsone (tryparsamide)

unknown active ✓ Verified May 2026

Tryparsone (generic name: tryparsamide) is a drug. It is currently in unknown development.

Tryparsone works by inhibiting the enzyme dihydrofolate reductase, which is essential for the survival of the trypanosome parasite.

Tryparsone is a small molecule. It is used to treat African trypanosomiasis, also known as sleeping sickness, according to ClinicalTrials.gov.

At a glance

Generic nametryparsamide
Therapeutic areaOther
Phaseunknown

Mechanism of action

Think of it like a key that fits into a lock. The lock is the enzyme dihydrofolate reductase, and the key is Tryparsone. When Tryparsone fits into the lock, it prevents the enzyme from working properly, which ultimately kills the parasite.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Tryparsone

What is Tryparsone?

Tryparsone (tryparsamide) is a pharmaceutical drug.

How does Tryparsone work?

Tryparsone works by inhibiting the enzyme dihydrofolate reductase, which is essential for the survival of the trypanosome parasite.

What is the generic name of Tryparsone?

tryparsamide is the generic (nonproprietary) name of Tryparsone.

What development phase is Tryparsone in?

Tryparsone is in unknown.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing