Last reviewed 2026-04-22 · How we verify

Trichosanthes root

Trichosanthes root contains bioactive compounds that exhibit anti-inflammatory, immunomodulatory, and potential antitumor properties through multiple cellular pathways.

Trichosanthes root contains bioactive compounds that exhibit anti-inflammatory, immunomodulatory, and potential antitumor properties through multiple cellular pathways. Used for Cancer (various types, traditional use in Chinese medicine), Inflammatory conditions.

At a glance

Mechanism of action

Trichosanthes root (from the plant Trichosanthes kirilowii) is a traditional Chinese medicine ingredient containing proteins, polysaccharides, and other phytochemicals that modulate immune function and inflammatory responses. Preclinical studies suggest it may inhibit tumor cell proliferation and induce apoptosis, though the exact molecular mechanisms remain incompletely characterized in clinical settings.

Approved indications

• Cancer (various types, traditional use in Chinese medicine)
• Inflammatory conditions

Common side effects

• Gastrointestinal disturbance
• Allergic reactions

Key clinical trials

• Effectiveness of Joins® for Managing Lumbar Facetogenic Pain (NA)
• The Effects of Trichosanthes Root on Blood Sugar in Patients With Diabetes Mellitus (PHASE2, PHASE3)

Primary sources

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Competitive intelligence

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