{"id":"trichosanthes-root","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Allergic reactions"}]},"_chembl":null,"_dailymed":{"setId":"d57fe444-5342-8a3f-e053-2995a90a6b25","title":"OKCHEONWON (TRICHOSANTHES KIRILOWII ROOT, PUERARIA LOBATA ROOT, LIRIOPE MUSCARI ROOT, OPHIOPOGON JAPONICUS ROOT, PRUNUS MUME FRUIT, ASTRAGALUS MONGHOLICUS ROOT, ASIAN GINSENG, LICORICE) PILL [CHUNWOO PHARMACEUTICAL CO., LTD.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Trichosanthes root (from the plant Trichosanthes kirilowii) is a traditional Chinese medicine ingredient containing proteins, polysaccharides, and other phytochemicals that modulate immune function and inflammatory responses. Preclinical studies suggest it may inhibit tumor cell proliferation and induce apoptosis, though the exact molecular mechanisms remain incompletely characterized in clinical settings.","oneSentence":"Trichosanthes root contains bioactive compounds that exhibit anti-inflammatory, immunomodulatory, and potential antitumor properties through multiple cellular pathways.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T02:11:21.321Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cancer (various types, traditional use in Chinese medicine)"},{"name":"Inflammatory conditions"}]},"trialDetails":[{"nctId":"NCT06204952","phase":"NA","title":"Effectiveness of Joins® for Managing Lumbar Facetogenic Pain","status":"NOT_YET_RECRUITING","sponsor":"Jeeyoun Moon","startDate":"2024-06-22","conditions":"Facet Joint Syndrome","enrollment":76},{"nctId":"NCT02855645","phase":"PHASE2, PHASE3","title":"The Effects of Trichosanthes Root on Blood Sugar in Patients With Diabetes Mellitus","status":"UNKNOWN","sponsor":"China Medical University Hospital","startDate":"2016-07","conditions":"Diabetes Mellitus","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":8,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Trichosanthes root","genericName":"Trichosanthes root","companyName":"China Medical University Hospital","companyId":"china-medical-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Trichosanthes root contains bioactive compounds that exhibit anti-inflammatory, immunomodulatory, and potential antitumor properties through multiple cellular pathways. Used for Cancer (various types, traditional use in Chinese medicine), Inflammatory conditions.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}