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Trichloracetic Acid (TRICHLOROACETIC ACID)
Trichloroacetic acid works by directly destroying infected cells on the skin's surface.
Trichloroacetic acid is a small molecule drug in the trichloroacetic acid class, originally developed by an unknown entity. It is used to treat Condyloma acuminatum, a sexually transmitted infection. The commercial status of trichloroacetic acid is unclear, but it is likely used as a generic medication. Key safety considerations include the potential for skin irritation and allergic reactions. Further research is needed to fully understand its pharmacokinetic properties.
At a glance
| Generic name | TRICHLOROACETIC ACID |
|---|---|
| Drug class | trichloroacetic acid |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | discontinued |
Mechanism of action
When applied topically, trichloroacetic acid penetrates the outer layers of the skin and causes the infected cells to die, effectively removing the visible signs of the infection. This process is often referred to as 'chemical peeling.' The acid's ability to selectively target and destroy infected cells makes it an effective treatment for Condyloma acuminatum.
Approved indications
- Condyloma acuminatum
Common side effects
Key clinical trials
- Comparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face Study (NA)
- Subcision Followed by Diluted Calcium Hydroxylapatite Injection Versus Subcision Followed by Painting CROSS TCA Technique for the Treatment of Atrophic Acne Scars (NA)
- PDT vs Peels for Treatment of Actinic Keratoses (PHASE2)
- TCA 15% Chemical Peel for Improvement in Hand Lentigines (PHASE4)
- Efficacy of 100% Trichloroacetic Acid Vs. Cryotherapy in Xanthelasma Palpebrarum (NA)
- Topical 15% Trichloroacetic Acid Versus Silver Nitrate Cauterization in the Management of Idiopathic Childhood Epistaxis: A Prospective Double-Blinded, Randomized Clinical Trial (NA)
- To Compare the Efficacy of Intralesional Saline Versus 35% Trichloracetic Acid (TCA) Peel in the Treatment of Atrophic Acne Scars (PHASE2)
- Efficacy of Topical 85% TCA in the Treatment of LSIL After Low-grade Abnormality of Screening Test: a Randomized Controlled Trial (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Trichloracetic Acid CI brief — competitive landscape report
- Trichloracetic Acid updates RSS · CI watch RSS