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transforaminal epidural injection.
transforaminal epidural injection. is a Small molecule drug developed by Beni-Suef University. It is currently FDA-approved for Radiculopathy due to disc herniation or spinal stenosis, Nerve root compression pain, Sciatica.
Transforaminal epidural injection delivers corticosteroids and/or local anesthetics directly into the epidural space via the intervertebral foramen to reduce inflammation and pain in nerve root compression.
A transforaminal epidural injection is a medical procedure used to treat conditions such as neuropathic pain from lumbosacral radiculopathy, chronic pain, and lumbar radiculopathy. The procedure typically involves injecting a solution, such as a compound solution of sodium chloride, into the epidural space through a foramen in the spine.
At a glance
| Generic name | transforaminal epidural injection. |
|---|---|
| Sponsor | Beni-Suef University |
| Modality | Small molecule |
| Therapeutic area | Pain Management / Neurology |
| Phase | FDA-approved |
Mechanism of action
This is a minimally invasive interventional procedure rather than a systemically administered drug. The injection targets the epidural space surrounding the spinal cord and nerve roots, delivering anti-inflammatory corticosteroids (commonly methylprednisolone or triamcinolone) and local anesthetics (typically lidocaine) to reduce inflammation, edema, and pain associated with nerve root irritation. The transforaminal approach allows direct access to the affected nerve root via the neural foramen.
Approved indications
- Radiculopathy due to disc herniation or spinal stenosis
- Nerve root compression pain
- Sciatica
Common side effects
- Transient increase in pain
- Headache
- Dizziness
- Infection at injection site
- Bleeding/hematoma
- Nerve injury
Key clinical trials
- Inflammatory Markers in Lumbar Radicular Pain Treated With PRF and TFESI
- Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain
- Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy (PHASE1)
- "Effectiveness of Physical Therapy Added to Transforaminal Injection in Lumbar Radicular Pain"
- Ultrasound Guided Cervical Selective Nerve Root Block Versus Fluoroscopic Guided Cervical Transforaminal Epidural Block (NA)
- Platelet Lysate vs Saline for Lumbosacral Radiculopathy (NA)
- PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation
- The Effect of Adding a Local Anesthetic to Transforaminal Epidural Injection in Cervical Disc Herniation. (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- transforaminal epidural injection. CI brief — competitive landscape report
- transforaminal epidural injection. updates RSS · CI watch RSS
- Beni-Suef University portfolio CI
Frequently asked questions about transforaminal epidural injection.
What is transforaminal epidural injection.?
How does transforaminal epidural injection. work?
What is transforaminal epidural injection. used for?
Who makes transforaminal epidural injection.?
What development phase is transforaminal epidural injection. in?
What are the side effects of transforaminal epidural injection.?
Related
- Manufacturer: Beni-Suef University — full pipeline
- Therapeutic area: All drugs in Pain Management / Neurology
- Indication: Drugs for Radiculopathy due to disc herniation or spinal stenosis
- Indication: Drugs for Nerve root compression pain
- Indication: Drugs for Sciatica
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing