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Tramadol Once A Day
Tramadol is a centrally acting opioid analgesic that works by binding to opioid receptors in the brain and spinal cord.
Tramadol is a centrally acting opioid analgesic that works by binding to opioid receptors in the brain and spinal cord. Used for Moderate to moderately severe pain, Severe pain.
At a glance
| Generic name | Tramadol Once A Day |
|---|---|
| Sponsor | Labopharm Inc. |
| Drug class | Opioid analgesic |
| Target | mu-opioid receptor |
| Modality | Small molecule |
| Therapeutic area | Pain management |
| Phase | Phase 3 |
Mechanism of action
This binding causes a decrease in the transmission of pain signals to the brain, resulting in pain relief. Tramadol also inhibits the reuptake of norepinephrine and serotonin, which can contribute to its analgesic effects.
Approved indications
- Moderate to moderately severe pain
- Severe pain
Common side effects
- Nausea
- Dizziness
- Headache
- Somnolence
- Constipation
- Vomiting
- Fatigue
- Dry mouth
- Sweating
- Rash
Key clinical trials
- ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
- Efficacy and Safety of Intravenous Dexamethasone Palmitate Treatments in Acute and Subacute Herpes Zoster Pain (NA)
- Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy (NA)
- Efficacy of Duloxetine in Conjunction With Tramadol for Chronic Cancer Pain (NA)
- Food Effect on PK of DW-1021 (Pelubiprofen 45 mg / Tramadol 45.9 mg) in Healthy Adults (PHASE1)
- A Study to Evaluate the Efficacy and Safety of HR18042 Tablets in the Treatment of Postoperative Pain of Impacted Tooth. (PHASE2)
- Transdermal Buprenorphine for the Treatment of Radiation-Induced Mucositis Pain in Head and Neck Cancer Patients (PHASE2)
- Transversalis Fascia Plane Block for Laparoscopic Inguinal Hernia Repair (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Tramadol Once A Day CI brief — competitive landscape report
- Tramadol Once A Day updates RSS · CI watch RSS
- Labopharm Inc. portfolio CI