Last reviewed 2026-05-27 · How we verify

Coly-Mycin S (tonzonium)

Par Sterile Products · FDA-approved active Under review Quality 35/100

Coly-Mycin S (generic name: tonzonium) is a tonzonium drug developed by Par Sterile Products. It is currently FDA-approved (first approved 1962) for Mastoidectomy Cavity Infections, Otitis externa.

Coly-Mycin S is a small molecule antibiotic used to treat conditions such as osteomyelitis and cystic fibrosis. It is administered either orally or intravenously, and its exact mechanism of action is not specified in the provided information.

At a glance

Generic name	tonzonium
Sponsor	Par Sterile Products
Drug class	tonzonium
Target	Insulin-degrading enzyme
Therapeutic area	Metabolic
Phase	FDA-approved
First approval	1962

Approved indications

Mastoidectomy Cavity Infections
Otitis externa

Common side effects

No common side effects on file.

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
FDA label	Mechanism, indications, dosing, boxed warnings, drug interactions

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Coly-Mycin S CI brief — competitive landscape report
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Frequently asked questions about Coly-Mycin S

What is Coly-Mycin S?

Coly-Mycin S (tonzonium) is a tonzonium drug developed by Par Sterile Products, indicated for Mastoidectomy Cavity Infections, Otitis externa.

What is Coly-Mycin S used for?

Coly-Mycin S is indicated for Mastoidectomy Cavity Infections, Otitis externa.

Who makes Coly-Mycin S?

Coly-Mycin S is developed and marketed by Par Sterile Products (see full Par Sterile Products pipeline at /company/par-sterile-products).

What is the generic name of Coly-Mycin S?

tonzonium is the generic (nonproprietary) name of Coly-Mycin S.

What drug class is Coly-Mycin S in?

Coly-Mycin S belongs to the tonzonium class. See all tonzonium drugs at /class/tonzonium.

When was Coly-Mycin S approved?

Coly-Mycin S was first approved on 1962.

What development phase is Coly-Mycin S in?

Coly-Mycin S is FDA-approved (marketed).

What does Coly-Mycin S target?

Coly-Mycin S targets Insulin-degrading enzyme and is a tonzonium.

Drug class: All tonzonium drugs
Target: All drugs targeting Insulin-degrading enzyme
Manufacturer: Par Sterile Products — full pipeline
Therapeutic area: All drugs in Metabolic
Indication: Drugs for Mastoidectomy Cavity Infections
Indication: Drugs for Otitis externa

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing