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TheraDerm

Massachusetts General Hospital · FDA-approved active Small molecule

TheraDerm is a topical immunotherapy that activates local immune responses to treat skin conditions.

TheraDerm is a topical immunotherapy that activates local immune responses to treat skin conditions. Used for Cutaneous T-cell lymphoma, Melanoma (cutaneous lesions).

At a glance

Generic nameTheraDerm
SponsorMassachusetts General Hospital
Drug classTopical immunotherapy
ModalitySmall molecule
Therapeutic areaDermatology/Oncology
PhaseFDA-approved

Mechanism of action

TheraDerm is designed to stimulate innate immune pathways in the skin, promoting anti-tumor or anti-inflammatory activity at the site of application. The exact molecular mechanism involves toll-like receptor activation or similar pattern recognition receptor signaling to enhance local immune cell infiltration and activation.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results