{"id":"theraderm","safety":{"commonSideEffects":[{"rate":null,"effect":"Local skin irritation"},{"rate":null,"effect":"Erythema"},{"rate":null,"effect":"Pruritus"}]},"_chembl":null,"_dailymed":{"setId":"1fea6ad8-4d33-4f7c-800c-1bee644bd97f","title":"THERADERM PLATINUM PROTECTION FACIAL SUNSCREEN SPF 40 (OCTOCRYLENE, OCTISALATE, ZINC OXIDE) LOTION [THERAPON INC]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"TheraDerm is designed to stimulate innate immune pathways in the skin, promoting anti-tumor or anti-inflammatory activity at the site of application. The exact molecular mechanism involves toll-like receptor activation or similar pattern recognition receptor signaling to enhance local immune cell infiltration and activation.","oneSentence":"TheraDerm is a topical immunotherapy that activates local immune responses to treat skin conditions.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T06:27:54.079Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cutaneous T-cell lymphoma"},{"name":"Melanoma (cutaneous lesions)"}]},"trialDetails":[{"nctId":"NCT00027430","phase":"NA","title":"Androgen Replacement Therapy in Women With Hypopituitarism","status":"COMPLETED","sponsor":"Massachusetts General Hospital","startDate":"2001-09","conditions":"Hypopituitarism","enrollment":50}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":3,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"TheraDerm","genericName":"TheraDerm","companyName":"Massachusetts General Hospital","companyId":"massachusetts-general-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"TheraDerm is a topical immunotherapy that activates local immune responses to treat skin conditions. Used for Cutaneous T-cell lymphoma, Melanoma (cutaneous lesions).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}