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Terbutaline sulphate
Terbutaline sulphate is a Beta-2 adrenergic receptor agonist Small molecule drug developed by AstraZeneca. It is currently in Phase 3 development for Asthma, Chronic obstructive pulmonary disease (COPD). Also known as: Terbutaline sulphate powder for inhalation, 0.5 mg (metered dose) terbutaline per inhalation, Terbutaline sulphate powder for inhalation, 0.4 mg (delivered dose) terbutaline per inhalation.
Terbutaline sulphate is a beta-2 adrenergic receptor agonist that works by stimulating the beta-2 receptors in the lungs to cause bronchodilation.
Terbutaline sulphate is a beta-2 adrenergic receptor agonist that works by stimulating the beta-2 receptors in the lungs to cause bronchodilation. Used for Asthma, Chronic obstructive pulmonary disease (COPD).
At a glance
| Generic name | Terbutaline sulphate |
|---|---|
| Also known as | Terbutaline sulphate powder for inhalation, 0.5 mg (metered dose) terbutaline per inhalation, Terbutaline sulphate powder for inhalation, 0.4 mg (delivered dose) terbutaline per inhalation |
| Sponsor | AstraZeneca |
| Drug class | Beta-2 adrenergic receptor agonist |
| Target | Beta-2 adrenergic receptor |
| Modality | Small molecule |
| Therapeutic area | Respiratory |
| Phase | Phase 3 |
Mechanism of action
This leads to relaxation of bronchial smooth muscle, resulting in increased airflow to the lungs and relief of bronchospasm symptoms. Terbutaline sulphate is a selective beta-2 agonist, which means it has a higher affinity for beta-2 receptors than beta-1 receptors, reducing the risk of cardiac side effects.
Approved indications
- Asthma
- Chronic obstructive pulmonary disease (COPD)
Common side effects
- Tremors
- Nervousness
- Headache
- Palpitations
- Dizziness
Key clinical trials
- Terbutaline Sulfate in Adults With Asthma (PHASE2, PHASE3)
- Hot Flashes and Neurovascular Function in Women (NA)
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
- Randomized Controlled Trial of Intravenous Magnesium Sulfate Versus Terbutaline for Children in the Management of Acute Exacerbation of Asthma (PHASE3)
- The Impact of Airway Allergic Diseases on Children's and Parents' Quality of Life
- Airway Microbiota Based Treatment of Asthma in Preschool Children (PHASE4)
- Umbilical Cord Mesenchymal Stem Cells Transplantation in the Treatment of Chronic Obstructive Pulmonary Disease (PHASE1, PHASE2)
- Pharmacodynamic Study of Carvedilol Versus Metoprolol in Heart Failure (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Terbutaline sulphate CI brief — competitive landscape report
- Terbutaline sulphate updates RSS · CI watch RSS
- AstraZeneca portfolio CI
Frequently asked questions about Terbutaline sulphate
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Related
- Drug class: All Beta-2 adrenergic receptor agonist drugs
- Target: All drugs targeting Beta-2 adrenergic receptor
- Manufacturer: AstraZeneca — full pipeline
- Therapeutic area: All drugs in Respiratory
- Indication: Drugs for Asthma
- Indication: Drugs for Chronic obstructive pulmonary disease (COPD)
- Also known as: Terbutaline sulphate powder for inhalation, 0.5 mg (metered dose) terbutaline per inhalation, Terbutaline sulphate powder for inhalation, 0.4 mg (delivered dose) terbutaline per inhalation
- Compare: Terbutaline sulphate vs similar drugs
- Pricing: Terbutaline sulphate cost, discount & access