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TAP Block and Dexamethasone i.v.
TAP block is a technique used to prevent postoperative shivering, while dexamethasone is a corticosteroid with anti-inflammatory and immunosuppressive properties.
TAP block is a technique used to prevent postoperative shivering, while dexamethasone is a corticosteroid with anti-inflammatory and immunosuppressive properties. Used for Prevention of postoperative shivering.
At a glance
| Generic name | TAP Block and Dexamethasone i.v. |
|---|---|
| Also known as | TAP-Block under ultrasound guidance and i.v. dexamethasone |
| Sponsor | San Salvatore Hospital of L'Aquila |
| Drug class | Local anesthetic, Corticosteroid |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | Phase 3 |
Mechanism of action
TAP block involves the injection of local anesthetics into the transversus abdominis plane to block nerve signals that cause shivering. Dexamethasone, on the other hand, is a synthetic corticosteroid that can reduce inflammation and suppress the immune system. When used together, they can help reduce the incidence of postoperative shivering and other complications.
Approved indications
- Prevention of postoperative shivering
Common side effects
- Hypertension
- Nausea and vomiting
- Headache
- Dizziness
- Insomnia
Key clinical trials
- Comparing Intravenous Magnesium Sulfate With Dexamethasone as Adjuvants to Ultrasound Guided TAPblock (NA)
- Dexamethasone Added in Ultrasound-guided Transversus Abdominis Plain Block for Postoperative Analgesia (PHASE3)
- A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- TAP Block and Dexamethasone i.v. CI brief — competitive landscape report
- TAP Block and Dexamethasone i.v. updates RSS · CI watch RSS
- San Salvatore Hospital of L'Aquila portfolio CI