Last reviewed 2026-04-20 · How we verify

Cialis (tadalafil)

At a glance

Approved indications

• Benign prostatic hyperplasia
• Impotence
• Pulmonary hypertension

Common side effects

• Headache
• Dyspepsia
• Back pain
• Myalgia
• Nasal congestion
• Flushing
• Pain in limb

Serious adverse events

• Gastroesophageal reflux disease
• Vomiting
• Arthralgia
• Muscle spasm

Key clinical trials

• Randomised Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma (Phase 3)
• Medication Facilitated Ureteral Access Sheath Deployment During Ureteroscopy and Endoscopic-Guided Percutaneous Nephrolithotomy: A Randomized Double-Blind Placebo Controlled Trial of Tadalafil, Tamsul (Phase 4)
• NCT03246880 (Phase 3)
• Pilot Study to Investigate the Effect of Tadalafil on Secondary Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease (NA)
• Phase I Trial of Chemoimmunotherapy and Hypofractionated Radiation Therapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma. (Phase 1)
• Do Phosphodiesterase 5A Inhibitors Improve Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease and Pulmonary Hypertension? (Phase 2)
• Efficacy of Tadalafil and Solifenacin Versus Tamsulosin and Solifenacin Combination Therapy for the Treatment of Benign Prostatic Hyperplasia With Overactive Bladder: A Randomized Controlled Trial (Phase 4)
• A Randomized, Open-label, Multiple Dosing, 2-way Crossover Study to Evaluate the Pharmacokinetic Effect of Tadalafil on Tamsulosin in Healthy Male Volunteers (Phase 1)

Patents

Primary sources

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