Last reviewed · How we verify
Supersaturated Calcium Phosphate
Supersaturated calcium phosphate releases bioavailable calcium and phosphate ions to remineralize and repair dental enamel and dentin.
Supersaturated calcium phosphate releases bioavailable calcium and phosphate ions to remineralize and repair dental enamel and dentin. Used for Dental enamel remineralization, Caries prevention and reversal of early caries lesions, Dentin hypersensitivity management.
At a glance
| Generic name | Supersaturated Calcium Phosphate |
|---|---|
| Also known as | Moistir (Kingswood laboratories Inc., Indianapolis IN USA) |
| Sponsor | Riyadh Colleges of Dentistry and Pharmacy |
| Drug class | Remineralizing agent |
| Modality | Small molecule |
| Therapeutic area | Dentistry |
| Phase | FDA-approved |
Mechanism of action
This product delivers calcium and phosphate in a supersaturated state, which promotes the deposition of mineral onto tooth surfaces and into demineralized lesions. By restoring mineral content, it helps reverse early enamel erosion and caries damage, and supports the structural integrity of dental tissues. The supersaturation state enhances bioavailability compared to conventional calcium phosphate formulations.
Approved indications
- Dental enamel remineralization
- Caries prevention and reversal of early caries lesions
- Dentin hypersensitivity management
Common side effects
Key clinical trials
- Caphosol Study: Prevention of Oral Mucositis in Children, Adolescents and Young Adults Receiving Chemotherapy (PHASE3)
- Supersaturated Calcium Phosphate Oral Rinse (Caphosol®) For the Prevention of Oral Mucositis in Children Undergoing Chemotherapeutic Treatments (PHASE2)
- Ectoin® Mouth Wash (EML03) in the Prevention and Treatment of Radiation-induced Oral Mucositis (NA)
- Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant (PHASE3)
- NeutraSal Treatment for Xerostomia in OSAS Patients Using CPAP Therapy (NA)
- Caphosol in Oral Mucositis Due to Targeted Therapy (PHASE3)
- Oral Hygiene Regimen in Patients on HCT (PHASE4)
- Caphosol® Versus State-of-the-art Mouthcare in Patients With Allogeneic Stem Cell Transplantation: a Randomized Controlled Study About the Efficacy of the Mouth Rinse Caphosol® (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape: