Placebo slurry

University of North Carolina, Chapel Hill · FDA-approved active Small molecule

Placebo slurry is a Small molecule drug developed by University of North Carolina, Chapel Hill. It is currently FDA-approved for Control agent in clinical trials. Also known as: Sucralose.

Placebo slurry produces therapeutic effects through the patient's expectation and belief in treatment, activating endogenous healing mechanisms.

Placebo slurry is an intervention used in clinical trials for various conditions, including Ulcerative Colitis, Celiac Disease, and Familial Adenomatous Polyposis. It is used as a control group in studies comparing it to other interventions, such as Fecal Microbiota Transplantation and Mesalamine Granules.

At a glance

Generic name	Placebo slurry
Also known as	Sucralose
Sponsor	University of North Carolina, Chapel Hill
Modality	Small molecule
Phase	FDA-approved

Mechanism of action

Placebo effects operate via psychological and neurobiological pathways, including expectation-driven activation of endogenous neurotransmitter systems and pain modulation circuits. The slurry formulation is an inert preparation designed to be administered as a control or comparative agent in clinical research. In marketed contexts, any therapeutic benefit derives from placebo response rather than active pharmacological mechanisms.

Approved indications

• Control agent in clinical trials

Common side effects

• Nocebo effects (adverse events attributed to placebo)

Key clinical trials

• The Effects of Kynurenine Aminotransferase Inhibition in People With Schizophrenia (PHASE1, PHASE2)
• Immunosafe-CeD: Are Partially Hydrolysed Gluten Harmful to Celiac Disease Patients? (NA)
• Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis Enhance Chemical Pleurodesis (PHASE4)
• An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel (NA)
• Seprafilm Slurry in the Prevention of Uterine Scarring in Patients Undergoing Hysteroscopic Myomectomy (PHASE4)
• In Situ Erosion Study to Investigate the Effectiveness of an Experimental Toothpaste (PHASE3)
• Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis (PHASE4)
• Fecal Microbiota Therapy Vs 5-aminosalicylates for Induction of Remission in Newly Diagnosed Mild-moderately Active UC (PHASE3)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• Placebo slurry CI brief — competitive landscape report
• Placebo slurry updates RSS · CI watch RSS
• University of North Carolina, Chapel Hill portfolio CI

Frequently asked questions about Placebo slurry

What is Placebo slurry?

Placebo slurry is a Small molecule drug developed by University of North Carolina, Chapel Hill, indicated for Control agent in clinical trials.

How does Placebo slurry work?

Placebo slurry produces therapeutic effects through the patient's expectation and belief in treatment, activating endogenous healing mechanisms.

What is Placebo slurry used for?

Placebo slurry is indicated for Control agent in clinical trials.

Who makes Placebo slurry?

Placebo slurry is developed and marketed by University of North Carolina, Chapel Hill (see full University of North Carolina, Chapel Hill pipeline at /company/university-of-north-carolina-chapel-hill).

Is Placebo slurry also known as anything else?

Placebo slurry is also known as Sucralose.

What development phase is Placebo slurry in?

Placebo slurry is FDA-approved (marketed).

What are the side effects of Placebo slurry?

Common side effects of Placebo slurry include Nocebo effects (adverse events attributed to placebo).

Related

• Manufacturer: University of North Carolina, Chapel Hill — full pipeline
• Indication: Drugs for Control agent in clinical trials
• Also known as: Sucralose