Last reviewed · How we verify

sub cutaneous liraglutide

Yaounde Central Hospital · FDA-approved active Small molecule

Liraglutide is a GLP-1 receptor agonist that mimics glucagon-like peptide-1 to stimulate insulin secretion, suppress glucagon, and slow gastric emptying.

Liraglutide is a GLP-1 receptor agonist that mimics glucagon-like peptide-1 to stimulate insulin secretion, suppress glucagon, and slow gastric emptying. Used for Type 2 diabetes mellitus, Weight management in obese or overweight patients.

At a glance

Generic namesub cutaneous liraglutide
Also known asVictoza
SponsorYaounde Central Hospital
Drug classGLP-1 receptor agonist
TargetGLP-1R
ModalitySmall molecule
Therapeutic areaDiabetes
PhaseFDA-approved

Mechanism of action

Liraglutide binds to and activates GLP-1 receptors on pancreatic beta cells, enhancing glucose-dependent insulin secretion. It also reduces glucagon secretion when blood glucose is elevated and delays gastric emptying, leading to reduced postprandial glucose excursions. These combined effects improve glycemic control in type 2 diabetes and promote modest weight loss.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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