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Short Term Effect of Liraglutide Versus Vildagliptine on Insulin Secretion and Insulin Sensitivity in a Sub Saharan African Population With Type 2 Diabetes (LIRAVIS)
This is a single blind randomised controlled clinical trial in uncontrolled type 2 Diabetes mellitus patients on oral glucose lowering agents, and naive to incretinomimetic. Participants will be randomised in two Arms : arm 1 receiving Liraglutide at 1,2 mg/day and arm 2 Vildagliptine at 100mg/day over 14 days. The two arms will be compared for 14-day changes in insulin secretion and insulin sensitivity.
Details
| Lead sponsor | Yaounde Central Hospital |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 14 |
| Start date | 2016-01 |
| Completion | 2016-12 |
Conditions
- Type 2 Diabetes Mellitus
Interventions
- sub cutaneous liraglutide
- Oral Vildagliptin
Primary outcomes
- Insulin sentivity — 2 weeks
2-week change in clamp-measured insulin sensitivity
Countries
Cameroon