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Standard of care antifungal prophylaxis
Standard of care antifungal prophylaxis is a Antifungal Small molecule drug developed by Fernanda P Silveira, MD, MS. It is currently in Phase 3 development for Prevention of invasive fungal infections in patients undergoing chemotherapy or hematopoietic stem cell transplantation. Also known as: Fluconazole, voriconazole, or no prophylaxis.
This drug works by inhibiting the growth of fungi.
This drug works by inhibiting the growth of fungi. Used for Prevention of invasive fungal infections in patients undergoing chemotherapy or hematopoietic stem cell transplantation.
At a glance
| Generic name | Standard of care antifungal prophylaxis |
|---|---|
| Also known as | Fluconazole, voriconazole, or no prophylaxis |
| Sponsor | Fernanda P Silveira, MD, MS |
| Drug class | Antifungal |
| Modality | Small molecule |
| Therapeutic area | Infectious Diseases |
| Phase | Phase 3 |
Mechanism of action
Standard of care antifungal prophylaxis drugs typically work by inhibiting the growth of fungi through various mechanisms, such as interfering with cell wall synthesis or inhibiting the production of essential nutrients. This can help prevent the spread of fungal infections in patients who are at high risk.
Approved indications
- Prevention of invasive fungal infections in patients undergoing chemotherapy or hematopoietic stem cell transplantation
Common side effects
- Nausea
- Diarrhea
- Vomiting
- Abdominal pain
- Headache
Key clinical trials
- Study of EL219 vs Standard of Care for Early Antifungal Therapy of Suspected Invasive Mould Infections (PHASE2)
- Platform Trial For Cryptococcal Meningitis (PHASE2, PHASE3)
- PTX3-targeted Antifungal Prophylaxis (NA)
- Rezafungin Prophylaxis in Liver Transplant (PHASE3)
- Single High-dose of Liposomal Amphotericin B in Combination With B/F/TAF for HIV/AIDS-associated Talaromycosis (NA)
- Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01) (PHASE3)
- Taxane Chemotherapy and Nail Toxicity in Women With Breast Cancer; Stage Two: Evaluation of Interventions (NA)
- β-D-Glucan (BDG) Surveillance With Preemptive Anidulafungin vs. Standard Care for Invasive Candidiasis in Surgical Intensive Care Unit (SICU) Patients (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Standard of care antifungal prophylaxis CI brief — competitive landscape report
- Standard of care antifungal prophylaxis updates RSS · CI watch RSS
- Fernanda P Silveira, MD, MS portfolio CI
Frequently asked questions about Standard of care antifungal prophylaxis
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Related
- Drug class: All Antifungal drugs
- Manufacturer: Fernanda P Silveira, MD, MS — full pipeline
- Therapeutic area: All drugs in Infectious Diseases
- Indication: Drugs for Prevention of invasive fungal infections in patients undergoing chemotherapy or hematopoietic stem cell transplantation
- Also known as: Fluconazole, voriconazole, or no prophylaxis
- Compare: Standard of care antifungal prophylaxis vs similar drugs
- Pricing: Standard of care antifungal prophylaxis cost, discount & access