Antifungal

This page covers all Antifungal drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Lanosterol 14α-demethylase, Ergosterol synthesis, Ergosterol, Sphingosine N-acyltransferase.

Targets

Lanosterol 14α-demethylase · Ergosterol synthesis · Ergosterol, Sphingosine N-acyltransferase · Enzyme · beta-glucan

Phase 3 pipeline (4)

• amorolfine 5% · Polichem S.A. · Dermatology
  Amorolfine is an antifungal agent that inhibits the growth of fungi by interfering with the synthesis of ergosterol, an essential component of fungal cell membranes.
• Standard of care antifungal prophylaxis · Fernanda P Silveira, MD, MS · Infectious Diseases
  This drug works by inhibiting the growth of fungi.
• amorolfine nail lacquer · Novartis · Dermatology
  Amorolfine nail lacquer works by inhibiting the growth of fungi on the nail plate and nail bed.
• liposomal amphotericin B + miltefosine · Drugs for Neglected Diseases · Infectious Diseases
  Liposomal amphotericin B targets fungal cell membranes, while miltefosine targets fungal cell membranes and inhibits sphingosine N-acyltransferase.

Phase 2 pipeline (2)

• Combined with voriconazole · LI YAN · Infectious Diseases
  This drug works by inhibiting the activity of a specific enzyme.
• CD101 · Cidara Therapeutics Inc. · Infectious Disease
  CD101 is a recombinant human monoclonal antibody targeting beta-glucan.