Last reviewed · How we verify
sodium carboximethycellulose
Sodium carboxymethylcellulose is a cellulose derivative that acts as a viscous, water-soluble polymer to provide lubrication, moisture retention, and protective coating of mucosal surfaces.
Sodium carboxymethylcellulose is a cellulose derivative that acts as a viscous, water-soluble polymer to provide lubrication, moisture retention, and protective coating of mucosal surfaces. Used for Dry eye syndrome (artificial tears), Oral mucositis protection, Gastrointestinal mucosal protection.
At a glance
| Generic name | sodium carboximethycellulose |
|---|---|
| Sponsor | Universidade Federal do Rio de Janeiro |
| Drug class | Cellulose derivative; lubricant and protective agent |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology; Gastroenterology; Dermatology |
| Phase | FDA-approved |
Mechanism of action
As an anionic polysaccharide, sodium carboxymethylcellulose (CMC-Na) forms a hydrophilic gel layer when dissolved in aqueous solutions. It is used topically or as an excipient to protect and lubricate mucous membranes, reduce friction, and maintain moisture. Its mechanism is primarily physical rather than pharmacological, making it suitable for ophthalmic, oral, and gastrointestinal applications.
Approved indications
- Dry eye syndrome (artificial tears)
- Oral mucositis protection
- Gastrointestinal mucosal protection
Common side effects
- Mild ocular irritation
- Transient blurred vision
- Allergic contact dermatitis (rare)
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- sodium carboximethycellulose CI brief — competitive landscape report
- sodium carboximethycellulose updates RSS · CI watch RSS
- Universidade Federal do Rio de Janeiro portfolio CI