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Silver nanoparticles mouthwash
Silver nanoparticles in mouthwash exert antimicrobial effects by disrupting bacterial cell membranes and inhibiting microbial growth in the oral cavity.
Silver nanoparticles in mouthwash exert antimicrobial effects by disrupting bacterial cell membranes and inhibiting microbial growth in the oral cavity. Used for Oral antimicrobial therapy for dental plaque and gingivitis prevention, Oral cavity infection management.
At a glance
| Generic name | Silver nanoparticles mouthwash |
|---|---|
| Also known as | AgNPs mouthwash |
| Sponsor | Can Tho University of Medicine and Pharmacy |
| Drug class | Antimicrobial nanoparticle |
| Modality | Small molecule |
| Therapeutic area | Dentistry / Oral Health |
| Phase | Phase 3 |
Mechanism of action
Silver nanoparticles are known to have broad-spectrum antimicrobial properties through multiple mechanisms including direct contact with bacterial cell walls, generation of reactive oxygen species, and interference with bacterial metabolism. When formulated as a mouthwash, they target oral pathogens responsible for dental plaque, gingivitis, and other oral infections. The nanoparticle formulation allows for enhanced bioavailability and contact with oral tissues.
Approved indications
- Oral antimicrobial therapy for dental plaque and gingivitis prevention
- Oral cavity infection management
Common side effects
- Oral irritation or staining
- Allergic sensitization
- Taste alteration
Key clinical trials
- Children Acceptance of AgNP Mouthwash Against Chlorhexidine Mouthwash (NA)
- The Comparative Effects of Using 0.12% Chlorhexidine and Silver Nanoparticles Mouthwashes in Medical Students (PHASE3)
- Evaluation of Silver Nanoparticles for the Prevention of COVID-19 (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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