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SII Yellow Fever Vaccine
This live attenuated yellow fever vaccine stimulates the immune system to produce antibodies and cellular immunity against yellow fever virus.
This live attenuated yellow fever vaccine stimulates the immune system to produce antibodies and cellular immunity against yellow fever virus. Used for Prevention of yellow fever in endemic regions and travelers to yellow fever-endemic areas.
At a glance
| Generic name | SII Yellow Fever Vaccine |
|---|---|
| Sponsor | Serum Institute of India Pvt. Ltd. |
| Drug class | Live attenuated vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
The vaccine contains a weakened strain of yellow fever virus (17D strain) that replicates in vaccinated individuals but does not cause disease in immunocompetent people. This triggers both humoral (antibody) and cell-mediated immune responses, providing long-term protection against infection with wild-type yellow fever virus. A single dose typically confers lifelong immunity in most recipients.
Approved indications
- Prevention of yellow fever in endemic regions and travelers to yellow fever-endemic areas
Common side effects
- Headache
- Myalgia
- Fever
- Injection site reaction
- Fatigue
Key clinical trials
- A Study of SII Yellow Fever Vaccine to Compare Safety and Immunogenicity With STAMARIL (PHASE3)
- A Study of SII Yellow Fever Vaccine to Compare Safety and Immunogenicity With STAMARIL® In Healthy Infants (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- SII Yellow Fever Vaccine CI brief — competitive landscape report
- SII Yellow Fever Vaccine updates RSS · CI watch RSS
- Serum Institute of India Pvt. Ltd. portfolio CI