{"id":"sii-yellow-fever-vaccine","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Headache"},{"rate":"10-30","effect":"Myalgia"},{"rate":"5-15","effect":"Fever"},{"rate":"5-10","effect":"Injection site reaction"},{"rate":"5-15","effect":"Fatigue"}]},"_chembl":{"chemblId":"CHEMBL2108816","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"The vaccine contains a weakened strain of yellow fever virus (17D strain) that replicates in vaccinated individuals but does not cause disease in immunocompetent people. This triggers both humoral (antibody) and cell-mediated immune responses, providing long-term protection against infection with wild-type yellow fever virus. A single dose typically confers lifelong immunity in most recipients.","oneSentence":"This live attenuated yellow fever vaccine stimulates the immune system to produce antibodies and cellular immunity against yellow fever virus.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:34:30.898Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of yellow fever in endemic regions and travelers to yellow fever-endemic areas"}]},"trialDetails":[{"nctId":"NCT05421611","phase":"PHASE3","title":"A Study of SII Yellow Fever Vaccine to Compare Safety and Immunogenicity With STAMARIL","status":"COMPLETED","sponsor":"Serum Institute of India Pvt. Ltd.","startDate":"2023-05-11","conditions":"Yellow Fever","enrollment":1824},{"nctId":"NCT05447377","phase":"PHASE3","title":"A Study of SII Yellow Fever Vaccine to Compare Safety and Immunogenicity With STAMARIL® In Healthy Infants","status":"UNKNOWN","sponsor":"Serum Institute of India Pvt. Ltd.","startDate":"2022-09-16","conditions":"Yellow Fever","enrollment":2216}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"SII Yellow Fever Vaccine","genericName":"SII Yellow Fever Vaccine","companyName":"Serum Institute of India Pvt. Ltd.","companyId":"serum-institute-of-india-pvt-ltd","modality":"Biologic","firstApprovalDate":"","aiSummary":"This live attenuated yellow fever vaccine stimulates the immune system to produce antibodies and cellular immunity against yellow fever virus. Used for Prevention of yellow fever in endemic regions and travelers to yellow fever-endemic areas.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}