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sclerotherapy with aethoxysclerol foam

Medical University of Vienna · FDA-approved active Small molecule

sclerotherapy with aethoxysclerol foam is a Sclerosing agent Small molecule drug developed by Medical University of Vienna. It is currently FDA-approved for Varicose veins of the lower extremities, Venous insufficiency.

Aethoxysclerol foam causes endothelial damage and thrombosis within varicose veins, leading to vessel fibrosis and obliteration.

Aethoxysclerol foam causes endothelial damage and thrombosis within varicose veins, leading to vessel fibrosis and obliteration. Used for Varicose veins of the lower extremities, Venous insufficiency.

At a glance

Generic namesclerotherapy with aethoxysclerol foam
SponsorMedical University of Vienna
Drug classSclerosing agent
ModalitySmall molecule
Therapeutic areaVascular/Dermatology
PhaseFDA-approved

Mechanism of action

Aethoxysclerol is a sclerosing agent that, when injected as a foam into varicose veins, damages the venous endothelium and triggers an inflammatory response. This results in thrombosis and subsequent fibrosis of the vessel wall, causing the vein to close and be reabsorbed by the body. The foam formulation increases contact surface area with the endothelium, enhancing efficacy compared to liquid formulations.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about sclerotherapy with aethoxysclerol foam

What is sclerotherapy with aethoxysclerol foam?

sclerotherapy with aethoxysclerol foam is a Sclerosing agent drug developed by Medical University of Vienna, indicated for Varicose veins of the lower extremities, Venous insufficiency.

How does sclerotherapy with aethoxysclerol foam work?

Aethoxysclerol foam causes endothelial damage and thrombosis within varicose veins, leading to vessel fibrosis and obliteration.

What is sclerotherapy with aethoxysclerol foam used for?

sclerotherapy with aethoxysclerol foam is indicated for Varicose veins of the lower extremities, Venous insufficiency.

Who makes sclerotherapy with aethoxysclerol foam?

sclerotherapy with aethoxysclerol foam is developed and marketed by Medical University of Vienna (see full Medical University of Vienna pipeline at /company/medical-university-of-vienna).

What drug class is sclerotherapy with aethoxysclerol foam in?

sclerotherapy with aethoxysclerol foam belongs to the Sclerosing agent class. See all Sclerosing agent drugs at /class/sclerosing-agent.

What development phase is sclerotherapy with aethoxysclerol foam in?

sclerotherapy with aethoxysclerol foam is FDA-approved (marketed).

What are the side effects of sclerotherapy with aethoxysclerol foam?

Common side effects of sclerotherapy with aethoxysclerol foam include Thrombophlebitis, Hyperpigmentation at injection site, Allergic reaction, Matting (fine telangiectasia), Neovascularization.

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