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S5G4T-2
S5G4T-2 is a topical gel formulation of a retinoid, which works by modulating the activity of retinoic acid receptors in the skin.
S5G4T-2 is a topical gel formulation of a retinoid, which works by modulating the activity of retinoic acid receptors in the skin. Used for Acne vulgaris.
At a glance
| Generic name | S5G4T-2 |
|---|---|
| Also known as | Vehicle cream |
| Sponsor | Sol-Gel Technologies, Ltd. |
| Drug class | Retinoid |
| Target | Retinoic acid receptors |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | Phase 3 |
Mechanism of action
By activating these receptors, S5G4T-2 helps to regulate the growth and differentiation of skin cells, leading to improved symptoms of acne and other skin conditions. This mechanism of action is similar to other retinoid-based treatments, but the topical gel formulation of S5G4T-2 allows for more targeted delivery and potentially reduced systemic side effects.
Approved indications
- Acne vulgaris
Common side effects
- Skin irritation
- Dry skin
- Redness
Key clinical trials
- A Study of S5G4T-1 in the Treatment of Papularpustular Rosacea (PHASE3)
- A Study of S5G4T-1 in the Treatment of Papulopustular Rosacea (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |