Last reviewed 2026-05-27 · How we verify

(-)-Nicardipine ((S)-nicardipine)

unknown active

(-)-Nicardipine (generic name: (S)-nicardipine) is a (S)-nicardipine drug. It is currently in unknown development.

Nicardipine works by blocking calcium channels to reduce blood pressure and heart rate.

-)-Nicardipine ((S)-nicardipine) is a small molecule drug that targets voltage-gated L-type calcium channels. It is a member of the dihydropyridine class of calcium channel blockers. The drug's commercial status and approved indications are unknown. Further research is needed to determine its safety profile and potential uses. As a calcium channel blocker, it works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells.

At a glance

Generic name	(S)-nicardipine
Drug class	(S)-nicardipine
Target	Voltage-gated L-type calcium channel
Therapeutic area	Cardiovascular
Phase	unknown

Mechanism of action

Imagine your heart and blood vessels are like a garden hose. Calcium ions help control how much water flows through the hose. Nicardipine acts like a valve that reduces the flow of calcium ions, making it easier for your heart to pump blood and your blood vessels to relax.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO) (PHASE3)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

(-)-Nicardipine CI brief — competitive landscape report
(-)-Nicardipine updates RSS · CI watch RSS
portfolio CI

Frequently asked questions about (-)-Nicardipine

What is (-)-Nicardipine?

(-)-Nicardipine ((S)-nicardipine) is a (S)-nicardipine drug.

How does (-)-Nicardipine work?

Nicardipine works by blocking calcium channels to reduce blood pressure and heart rate.

What is the generic name of (-)-Nicardipine?

(S)-nicardipine is the generic (nonproprietary) name of (-)-Nicardipine.

What drug class is (-)-Nicardipine in?

(-)-Nicardipine belongs to the (S)-nicardipine class. See all (S)-nicardipine drugs at /class/s-nicardipine.

What development phase is (-)-Nicardipine in?

(-)-Nicardipine is in unknown.

What does (-)-Nicardipine target?

(-)-Nicardipine targets Voltage-gated L-type calcium channel and is a (S)-nicardipine.

Drug class: All (S)-nicardipine drugs
Target: All drugs targeting Voltage-gated L-type calcium channel
Manufacturer: — full pipeline
Therapeutic area: All drugs in Cardiovascular

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing