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Rutin + Vitamin C
Rutin and Vitamin C work synergistically as antioxidants to reduce oxidative stress and strengthen vascular integrity through free radical scavenging and collagen stabilization.
Rutin and Vitamin C work synergistically as antioxidants to reduce oxidative stress and strengthen vascular integrity through free radical scavenging and collagen stabilization. Used for Venous insufficiency and capillary fragility, Hemorrhoids, Varicose veins.
At a glance
| Generic name | Rutin + Vitamin C |
|---|---|
| Also known as | Ruta C |
| Sponsor | Ain Shams University |
| Drug class | Antioxidant combination / Nutraceutical |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular / Vascular health |
| Phase | FDA-approved |
Mechanism of action
Rutin is a bioflavonoid that acts as a potent antioxidant and strengthens capillary walls by stabilizing collagen and reducing vascular permeability. Vitamin C (ascorbic acid) enhances this effect by regenerating rutin's antioxidant capacity and serving as a cofactor for collagen synthesis. Together, they reduce oxidative damage and improve microvascular function.
Approved indications
- Venous insufficiency and capillary fragility
- Hemorrhoids
- Varicose veins
- General antioxidant support
Common side effects
- Gastrointestinal upset
- Headache
- Dizziness
Key clinical trials
- Rutin and Vitamin C in Patients With Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) (PHASE2)
- Assessing the Quality of Life of Patients With Rosacea (NA)
- Evaluation of The Effect of Rutin and Vitamin C on the Oxidative Stress in Hemodialysis Patients (PHASE3)
- Impact of Rutin and Vitamin C Combination on Oxidative Stress, Insulin Sensitivity and Lipid Profile in Type 2 Diabetic Patients (PHASE2, PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Rutin + Vitamin C CI brief — competitive landscape report
- Rutin + Vitamin C updates RSS · CI watch RSS
- Ain Shams University portfolio CI