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Rotavirus Vaccine & Breastfeeding
The Rotavirus Vaccine works by stimulating the body's immune system to produce antibodies against rotavirus, thereby preventing infection.
The Rotavirus Vaccine works by stimulating the body's immune system to produce antibodies against rotavirus, thereby preventing infection. Used for Prevention of severe rotavirus gastroenteritis in infants and young children.
At a glance
| Generic name | Rotavirus Vaccine & Breastfeeding |
|---|---|
| Sponsor | International Centre for Diarrhoeal Disease Research, Bangladesh |
| Modality | Biologic |
| Therapeutic area | Infectious Diseases |
| Phase | Phase 3 |
Mechanism of action
This vaccine contains inactivated rotavirus particles that are unable to cause disease but can still trigger an immune response. The immune system recognizes these particles as foreign and mounts a response, producing antibodies that can neutralize and remove any future rotavirus infections.
Approved indications
- Prevention of severe rotavirus gastroenteritis in infants and young children
Common side effects
- Fever
- Redness, swelling, or pain at the injection site
- Vomiting
- Diarrhea
- Abdominal pain
Key clinical trials
- Reduction of Pain in Childhood Vaccination in the Primary Care Nurse Vaccination Consultation (NA)
- The Influence of the Microbiome on Rotavirus Vaccine Immunogenic Response in Infants in Karachi, Pakistan
- Immunogenicity of Rotavirus Vaccine (PHASE4)
- Predictors of Poor Immune Response to Rotavirus Vaccine in Infants (NA)
- Improving Rotavirus Vaccine Immune Response (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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