{"id":"rotavirus-vaccine-breastfeeding","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Fever"},{"rate":"5-10%","effect":"Redness, swelling, or pain at the injection site"},{"rate":"5-10%","effect":"Vomiting"},{"rate":"5-10%","effect":"Diarrhea"},{"rate":"5-10%","effect":"Abdominal pain"}]},"_chembl":{"chemblId":"CHEMBL2108573","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This vaccine contains inactivated rotavirus particles that are unable to cause disease but can still trigger an immune response. The immune system recognizes these particles as foreign and mounts a response, producing antibodies that can neutralize and remove any future rotavirus infections.","oneSentence":"The Rotavirus Vaccine works by stimulating the body's immune system to produce antibodies against rotavirus, thereby preventing infection.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:32:52.652Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of severe rotavirus gastroenteritis in infants and young children"}]},"trialDetails":[{"nctId":"NCT06004258","phase":"NA","title":"Reduction of Pain in Childhood Vaccination in the Primary Care Nurse Vaccination Consultation","status":"COMPLETED","sponsor":"Hospital Universitario Virgen Macarena","startDate":"2022-06-21","conditions":"Pain","enrollment":495},{"nctId":"NCT03031743","phase":"","title":"The Influence of the Microbiome on Rotavirus Vaccine Immunogenic Response in Infants in Karachi, Pakistan","status":"COMPLETED","sponsor":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","startDate":"2014-01","conditions":"Rotavirus","enrollment":88},{"nctId":"NCT01199874","phase":"PHASE4","title":"Immunogenicity of Rotavirus Vaccine","status":"COMPLETED","sponsor":"PATH","startDate":"2011-04","conditions":"Rotavirus Gastroenteritis","enrollment":1140},{"nctId":"NCT01700127","phase":"NA","title":"Predictors of Poor Immune Response to Rotavirus Vaccine in Infants","status":"COMPLETED","sponsor":"Society for Applied Studies","startDate":"2012-10","conditions":"Innate Immune Response","enrollment":400},{"nctId":"NCT01825109","phase":"PHASE3","title":"Improving Rotavirus Vaccine Immune Response","status":"COMPLETED","sponsor":"International Centre for Diarrhoeal Disease Research, Bangladesh","startDate":"2010-07","conditions":"Healthy Infants, Mothers","enrollment":300}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":104,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Rotavirus Vaccine & Breastfeeding","genericName":"Rotavirus Vaccine & Breastfeeding","companyName":"International Centre for Diarrhoeal Disease Research, Bangladesh","companyId":"international-centre-for-diarrhoeal-disease-research-bangladesh","modality":"Biologic","firstApprovalDate":"","aiSummary":"The Rotavirus Vaccine works by stimulating the body's immune system to produce antibodies against rotavirus, thereby preventing infection. Used for Prevention of severe rotavirus gastroenteritis in infants and young children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}