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Avandia (ROSIGLITAZONE)

Woodward · FDA-approved withdrawn Small molecule Under review Quality 50/100

Avandia (generic name: ROSIGLITAZONE) is a Peroxisome Proliferator Receptor gamma Agonist Small molecule drug developed by Woodward. It is currently FDA-approved (first approved 1999) for Treatment Refractory Type 2 Diabetes Mellitus.

Avandia, also known as rosiglitazone, is a small molecule that acts as a peroxisome proliferator-activated receptor gamma agonist. It has been studied for use in treating conditions such as Type 2 Diabetes and Asthma, and has been used in combination with other medications like insulin glargine and metformin.

At a glance

Generic nameROSIGLITAZONE
SponsorWoodward
Drug classPeroxisome Proliferator Receptor gamma Agonist
TargetCDGSH iron-sulfur domain-containing protein 1
ModalitySmall molecule
Therapeutic areaMetabolic
PhaseFDA-approved
First approval1999

Approved indications

Common side effects

Serious adverse events

Drug interactions

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
FDA labelMechanism, indications, dosing, boxed warnings, drug interactions
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Avandia

What is Avandia?

Avandia (ROSIGLITAZONE) is a Peroxisome Proliferator Receptor gamma Agonist drug developed by Woodward, indicated for Treatment Refractory Type 2 Diabetes Mellitus.

What is Avandia used for?

Avandia is indicated for Treatment Refractory Type 2 Diabetes Mellitus.

Who makes Avandia?

Avandia is developed and marketed by Woodward (see full Woodward pipeline at /company/woodward).

What is the generic name of Avandia?

ROSIGLITAZONE is the generic (nonproprietary) name of Avandia.

What drug class is Avandia in?

Avandia belongs to the Peroxisome Proliferator Receptor gamma Agonist class. See all Peroxisome Proliferator Receptor gamma Agonist drugs at /class/peroxisome-proliferator-receptor-gamma-agonist.

When was Avandia approved?

Avandia was first approved on 1999.

What development phase is Avandia in?

Avandia is FDA-approved (marketed).

What are the side effects of Avandia?

Common side effects of Avandia include Nausea/Vomiting, Anemia, Edema, Diarrhea, Headache, Dyspepsia. Serious adverse events: Congestive Heart Failure, Myocardial Infarction, Myocardial Ischemia, Sudden Death.

What does Avandia target?

Avandia targets CDGSH iron-sulfur domain-containing protein 1 and is a Peroxisome Proliferator Receptor gamma Agonist.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing