Last reviewed · How we verify
Treatment Refractory Type 2 Diabetes Mellitus
Approved treatments
- Amaryl · Sanofi
Amaryl works by binding to the sulfonylurea receptor 1 (SUR1) and Kir6.2 subunit of the ATP-sensitive potassium channel, closing the channel and depolarizing the pancreatic beta cell membrane, leading to insulin release. - Avandia · Woodward
- Glucophage · Generic (originally Merck Serono/Lipha)
Activates AMP-activated protein kinase (AMPK) to reduce hepatic glucose production and improve insulin sensitivity without causing hypoglycemia. - Glucophage · Dr. Reddy's Laboratories Limited
Clinical guidelines
- FDA label — 2L+
ZITUVIMET can be used in patients with treatment-refractory type 2 diabetes mellitus.
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Treatment Refractory Type 2 Diabetes Mellitus patent landscape — cliff calendar, originator estates, attackable patents
- Treatment Refractory Type 2 Diabetes Mellitus treatment landscape brief
- Treatment Refractory Type 2 Diabetes Mellitus treatment updates RSS
Frequently asked questions about Treatment Refractory Type 2 Diabetes Mellitus
What drugs treat Treatment Refractory Type 2 Diabetes Mellitus?
Tracked treatments include Amaryl, Avandia, Glucophage.
What is the treatment for Treatment Refractory Type 2 Diabetes Mellitus?
Standard treatment for Treatment Refractory Type 2 Diabetes Mellitus includes Amaryl, Avandia, Glucophage. See the treatment landscape page for first-line, second-line and salvage options.
What are the treatment guidelines for Treatment Refractory Type 2 Diabetes Mellitus?
FDA label publishes guidelines for Treatment Refractory Type 2 Diabetes Mellitus. 1 guideline references tracked.
Related
- Treatment landscape: Treatment Refractory Type 2 Diabetes Mellitus patent cliff · Treatment Refractory Type 2 Diabetes Mellitus CI report
- Treatment: Amaryl · Sanofi
- Treatment: Avandia · Woodward
- Treatment: Glucophage · Generic (originally Merck Serono/Lipha)
- Treatment: Glucophage · Dr. Reddy's Laboratories Limited
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing