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ropivacaine, ketorelac and epinephrine
ropivacaine, ketorelac and epinephrine is a Local anesthetic and NSAID Small molecule drug developed by Region Örebro County. It is currently in Phase 3 development for Postoperative pain management, Pain management during labor and delivery. Also known as: Narop, Toradol and adrenaline.
Ropivacaine is a local anesthetic that blocks nerve impulses, while ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, and epinephrine is a vasoconstrictor that helps to prolong the duration of action of ropivacaine.
Ropivacaine is a local anesthetic that blocks nerve impulses, while ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, and epinephrine is a vasoconstrictor that helps to prolong the duration of action of ropivacaine. Used for Postoperative pain management, Pain management during labor and delivery.
At a glance
| Generic name | ropivacaine, ketorelac and epinephrine |
|---|---|
| Also known as | Narop, Toradol and adrenaline |
| Sponsor | Region Örebro County |
| Drug class | Local anesthetic and NSAID |
| Target | Sodium channels and prostaglandin synthesis |
| Modality | Small molecule |
| Therapeutic area | Pain management |
| Phase | Phase 3 |
Mechanism of action
Ropivacaine works by inhibiting the sodium channels in nerve fibers, which prevents the transmission of pain signals to the brain. Ketorolac, on the other hand, blocks the production of prostaglandins, which are chemical mediators of pain and inflammation. Epinephrine helps to constrict blood vessels, which reduces bleeding and prolongs the duration of action of ropivacaine.
Approved indications
- Postoperative pain management
- Pain management during labor and delivery
Common side effects
- Nausea
- Vomiting
- Dizziness
- Headache
- Hypertension
Key clinical trials
- Local Infiltration Analgesia After Abdominal Hysterectomy (PHASE3)
- Local Infiltration Analgesia Following Unicompartmental Knee Arthroplasty (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- ropivacaine, ketorelac and epinephrine CI brief — competitive landscape report
- ropivacaine, ketorelac and epinephrine updates RSS · CI watch RSS
- Region Örebro County portfolio CI
Frequently asked questions about ropivacaine, ketorelac and epinephrine
What is ropivacaine, ketorelac and epinephrine?
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Related
- Drug class: All Local anesthetic and NSAID drugs
- Target: All drugs targeting Sodium channels and prostaglandin synthesis
- Manufacturer: Region Örebro County — full pipeline
- Therapeutic area: All drugs in Pain management
- Indication: Drugs for Postoperative pain management
- Indication: Drugs for Pain management during labor and delivery
- Also known as: Narop, Toradol and adrenaline
- Compare: ropivacaine, ketorelac and epinephrine vs similar drugs
- Pricing: ropivacaine, ketorelac and epinephrine cost, discount & access