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Rocuronium 0.8
Rocuronium is a non-depolarizing neuromuscular blocking agent that competitively inhibits nicotinic acetylcholine receptors at the neuromuscular junction.
Rocuronium is a non-depolarizing neuromuscular blocking agent that competitively inhibits nicotinic acetylcholine receptors at the neuromuscular junction. Used for Endotracheal intubation, Surgical procedures requiring muscle relaxation.
At a glance
| Generic name | Rocuronium 0.8 |
|---|---|
| Sponsor | Ain Shams University |
| Drug class | Non-depolarizing neuromuscular blocking agent |
| Target | Nicotinic acetylcholine receptor |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | Phase 3 |
Mechanism of action
This inhibition prevents acetylcholine from binding to its receptor, leading to muscle paralysis. The effect is reversible with anticholinesterases or by allowing time for spontaneous recovery.
Approved indications
- Endotracheal intubation
- Surgical procedures requiring muscle relaxation
Common side effects
- Hypotension
- Bradycardia
- Respiratory depression
- Anaphylaxis
Key clinical trials
- Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement (PHASE4)
- The Effect of Sedoanalgesia and General Anaesthesia on Early Neurological Recovery in Acute Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy (NA)
- Comparison of Hemodynamic Stability During Anesthesia Using Remimazolam and Sevoflurane in Minimally Invasive AVR (NA)
- Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy (NA)
- The Immune Response of Breast Cancer Patients Treated With Levobupivacaine Using Paravertebral or Superficial Chest Blocks (NA)
- Comparison of Spinal Anesthesia Adjuvant and Quadratus Lumborum Block on the Opioid Requirement and Perioperative Pain of Laparoscopic Kidney Transplant Donor (NA)
- Intubation Conditions After RSI Using Rocuronium with Ephedrine Pretreatment (PHASE3)
- Autonomic Dysfunction and Hemodynamic Instability During Per-oral Endoscopic Myotomy
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Rocuronium 0.8 CI brief — competitive landscape report
- Rocuronium 0.8 updates RSS · CI watch RSS
- Ain Shams University portfolio CI