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Resveratrol nasal spray

University of Campania Luigi Vanvitelli · Phase 3 active Small molecule

Resveratrol nasal spray is a Polyphenolic antioxidant Small molecule drug developed by University of Campania Luigi Vanvitelli. It is currently in Phase 3 development for Neurodegenerative disease or cognitive decline (investigational), Inflammatory or oxidative stress-related nasal/respiratory conditions (investigational).

Resveratrol is a polyphenolic antioxidant that activates sirtuins and other cellular pathways to reduce inflammation and oxidative stress.

Resveratrol is a polyphenolic antioxidant that activates sirtuins and other cellular pathways to reduce inflammation and oxidative stress. Used for Neurodegenerative disease or cognitive decline (investigational), Inflammatory or oxidative stress-related nasal/respiratory conditions (investigational).

At a glance

Generic nameResveratrol nasal spray
SponsorUniversity of Campania Luigi Vanvitelli
Drug classPolyphenolic antioxidant
TargetSIRT1, NF-κB pathway
ModalitySmall molecule
Therapeutic areaNeurology, Inflammation, Respiratory
PhasePhase 3

Mechanism of action

Resveratrol is a natural polyphenol found in grapes and other plants that acts as an antioxidant and anti-inflammatory agent. It activates sirtuin proteins (particularly SIRT1) and other cellular signaling pathways involved in stress resistance and longevity. When delivered intranasally, it may provide direct access to nasal and potentially systemic tissues to modulate inflammatory and oxidative processes.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Resveratrol nasal spray

What is Resveratrol nasal spray?

Resveratrol nasal spray is a Polyphenolic antioxidant drug developed by University of Campania Luigi Vanvitelli, indicated for Neurodegenerative disease or cognitive decline (investigational), Inflammatory or oxidative stress-related nasal/respiratory conditions (investigational).

How does Resveratrol nasal spray work?

Resveratrol is a polyphenolic antioxidant that activates sirtuins and other cellular pathways to reduce inflammation and oxidative stress.

What is Resveratrol nasal spray used for?

Resveratrol nasal spray is indicated for Neurodegenerative disease or cognitive decline (investigational), Inflammatory or oxidative stress-related nasal/respiratory conditions (investigational).

Who makes Resveratrol nasal spray?

Resveratrol nasal spray is developed by University of Campania Luigi Vanvitelli (see full University of Campania Luigi Vanvitelli pipeline at /company/university-of-campania-luigi-vanvitelli).

What drug class is Resveratrol nasal spray in?

Resveratrol nasal spray belongs to the Polyphenolic antioxidant class. See all Polyphenolic antioxidant drugs at /class/polyphenolic-antioxidant.

What development phase is Resveratrol nasal spray in?

Resveratrol nasal spray is in Phase 3.

What are the side effects of Resveratrol nasal spray?

Common side effects of Resveratrol nasal spray include Nasal irritation, Headache, Gastrointestinal effects (if systemic absorption).

What does Resveratrol nasal spray target?

Resveratrol nasal spray targets SIRT1, NF-κB pathway and is a Polyphenolic antioxidant.

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